Detalhe da pesquisa
1.
Cognitive and psychiatric adverse events during adjunctive cenobamate treatment in phase 2 and phase 3 clinical studies.
Epilepsy Behav
; 151: 109605, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38184949
2.
Sudden unexpected death in epilepsy during cenobamate clinical development.
Epilepsia
; 64(8): 2108-2115, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37219391
3.
Sustainability of seizure reduction and seizure control with adjunctive cenobamate: Post hoc analysis of a phase 3, open-label study.
Epilepsia
; 64(10): 2644-2652, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37497579
4.
Long-term individual retention with cenobamate in adults with focal seizures: Pooled data from the clinical development program.
Epilepsia
; 63(1): 139-149, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34813673
5.
Onset of efficacy and adverse events during Cenobamate titration period.
Acta Neurol Scand
; 146(3): 265-275, 2022 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-35711112
6.
Assessment of the long-term efficacy and safety of adjunctive perampanel in adolescent patients with epilepsy: Post hoc analysis of open-label extension studies.
Epilepsy Behav
; 135: 108901, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36122531
7.
Long-term safety of adjunctive cenobamate in patients with uncontrolled focal seizures: Open-label extension of a randomized clinical study.
Epilepsia
; 62(9): 2142-2150, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34254673
8.
Post hoc analysis of a phase 3, multicenter, open-label study of cenobamate for treatment of uncontrolled focal seizures: Effects of dose adjustments of concomitant antiseizure medications.
Epilepsia
; 62(12): 3016-3028, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34633074
9.
Efficacy of cenobamate for uncontrolled focal seizures: Post hoc analysis of a Phase 3, multicenter, open-label study.
Epilepsia
; 62(12): 3005-3015, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34633084
10.
Practical guidance for the management of adults receiving adjunctive cenobamate for the treatment of focal epilepsy-expert opinion.
Epilepsy Behav
; 123: 108270, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34509033
11.
Cenobamate (YKP3089) as adjunctive treatment for uncontrolled focal seizures in a large, phase 3, multicenter, open-label safety study.
Epilepsia
; 61(6): 1099-1108, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32396252
12.
Expert opinion: Proposed diagnostic and treatment algorithms for Lennox-Gastaut syndrome in adult patients.
Epilepsy Behav
; 110: 107146, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32563898
13.
Efficacy and safety of adjunctive perampanel in adolescent patients with epilepsy: Post hoc analysis of six randomized studies.
Epilepsy Behav
; 104(Pt A): 106876, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31954998
14.
A global update on cenobamate based on real-world experience in over 100 000 patients.
Epilepsia
; 65(4): 1149-1150, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38446133
15.
Safety and efficacy of adjunctive lacosamide among patients with partial-onset seizures in a long-term open-label extension trial of up to 8 years.
Epilepsy Behav
; 41: 164-70, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25461210
16.
A novel design for a dose finding, safety, and drug interaction study of an antiepileptic drug (retigabine) in early clinical development.
Int J Clin Pharmacol Ther
; 52(6): 509-18, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24755135
17.
Reductions in concomitant antiseizure medication drug load during adjunctive cenobamate therapy: Post-hoc analysis of a subset of patients from a phase 3, multicenter, open-label study.
Epilepsy Res
; 200: 107306, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38340681
18.
Safety and Efficacy of Cenobamate for the Treatment of Focal Seizures in Older Patients: Post Hoc Analysis of a Phase III, Multicenter, Open-Label Study.
Drugs Aging
; 41(3): 251-260, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38446341
19.
Kv7 potassium channel activation with ICA-105665 reduces photoparoxysmal EEG responses in patients with epilepsy.
Epilepsia
; 54(8): 1437-43, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23692516
20.
Pharmacokinetics of cenobamate as monotherapy compared with adjunctive therapy.
Epilepsy Res
; 195: 107185, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37429218